Umesh T Sankpal Selected Research

tolfenamic acid

2/2020	Next generation sequencing and functional pathway analysis to understand the mechanism of action of copper-tolfenamic acid against pancreatic cancer cells.
7/2019	Combination of clotam and vincristine enhances anti-proliferative effect in medulloblastoma cells.
1/2019	Clotam enhances anti-proliferative effect of vincristine in Ewing sarcoma cells.
1/2019	Copper-tolfenamic acid: evaluation of stability and anti-cancer activity.
1/2018	Novel Survivin Inhibitor for Suppressing Pancreatic Cancer Cells Growth via Downregulating Sp1 and Sp3 Transcription Factors.
2/2017	Tolfenamic acid-induced alterations in genes and pathways in pancreatic cancer cells.
1/2017	Targeting specificity protein 1 transcription factor and survivin using tolfenamic acid for inhibiting Ewing sarcoma cell growth.
10/2016	Association of Sp1 and survivin in epithelial ovarian cancer: Sp1 inhibitor and cisplatin, a novel combination for inhibiting epithelial ovarian cancer cell proliferation.
1/2016	Combination of tolfenamic acid and curcumin induces colon cancer cell growth inhibition through modulating specific transcription factors and reactive oxygen species.
1/2016	Small molecule tolfenamic acid and dietary spice curcumin treatment enhances antiproliferative effect in pancreatic cancer cells via suppressing Sp1, disrupting NF-kB translocation to nucleus and cell cycle phase distribution.

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Umesh T Sankpal Research Topics

Disease

26	Neoplasms (Cancer) 02/2020 - 01/2004
6	Pancreatic Neoplasms (Pancreatic Cancer) 02/2020 - 01/2012
5	Carcinogenesis 10/2012 - 09/2011
4	Neoplasm Metastasis (Metastasis) 11/2012 - 07/2009
3	Neuroblastoma 11/2015 - 05/2013
2	Medulloblastoma 07/2019 - 10/2013
2	Ewing Sarcoma (Sarcoma, Ewing) 01/2019 - 01/2017
2	Prostatic Neoplasms (Prostate Cancer) 11/2012 - 09/2011
2	Lung Neoplasms (Lung Cancer) 10/2012 - 01/2011
2	Esophageal Neoplasms (Esophageal Cancer) 09/2012 - 06/2012
2	Glioma (Gliomas) 10/2009 - 01/2009
2	Brain Neoplasms (Brain Tumor) 10/2009 - 01/2009
2	variable Immunodeficiency syndrome 05/2004 - 01/2004
1	Ovarian Epithelial Carcinoma 10/2016
1	Colorectal Neoplasms (Colorectal Cancer) 01/2016
1	Colonic Neoplasms (Colon Cancer) 01/2016
1	Leukemia 06/2014
1	Adenocarcinoma 01/2012
1	Ovarian Neoplasms (Ovarian Cancer) 07/2011
1	Chronic Disease (Chronic Diseases) 01/2011
1	Pain (Aches) 01/2011
1	Inflammation (Inflammations) 01/2011
1	Breast Neoplasms (Breast Cancer) 07/2009
1	Glioblastoma (Glioblastoma Multiforme) 01/2009
1	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2008
1	Genomic Instability 01/2004

Drug/Important Bio-Agent (IBA)

21	tolfenamic acidIBA 02/2020 - 01/2011
11	SurvivinIBA 07/2019 - 07/2011
11	Proteins (Proteins, Gene)FDA Link 01/2018 - 07/2009
10	Pharmaceutical PreparationsIBA 01/2019 - 01/2008
6	Transcription Factors (Transcription Factor)IBA 01/2018 - 09/2011
5	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 06/2018 - 01/2011
5	Sp Transcription FactorsIBA 06/2014 - 07/2011
3	CurcuminIBA 01/2016 - 01/2012
3	CarcinogensIBA 10/2012 - 09/2011
3	nitrosobenzylmethylamineIBA 09/2012 - 09/2011
3	Potassium Channels (Potassium Channel)IBA 10/2009 - 01/2009
3	DNA (Deoxyribonucleic Acid)IBA 01/2008 - 01/2004
3	MethyltransferasesIBA 01/2008 - 01/2004
2	CopperIBA 02/2020 - 01/2019
2	Vincristine (Oncovin)FDA LinkGeneric 07/2019 - 01/2019
2	Trastuzumab (Herceptin)FDA Link 10/2009 - 01/2009
2	Carboplatin (JM8)FDA LinkGeneric 10/2009 - 01/2009
2	Temozolomide (Temodar)FDA LinkGeneric 10/2009 - 01/2009
1	Apoptosis Regulatory ProteinsIBA 01/2018
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 02/2017
1	Sp1 Transcription FactorIBA 01/2017
1	Cisplatin (Platino)FDA LinkGeneric 10/2016
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2016
1	NF-kappa B (NF-kB)IBA 01/2016
1	Isotretinoin (Accutane)FDA LinkGeneric 11/2015
1	Inhibitor of Apoptosis ProteinsIBA 06/2014
1	Annexin A5IBA 05/2013
1	Biological ProductsIBA 05/2013
1	Coal (Coals)IBA 10/2012
1	DNA AdductsIBA 10/2012
1	Heavy MetalsIBA 10/2012
1	AsbestosIBA 10/2012
1	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA 10/2012
1	IsoenzymesIBA 09/2012
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 09/2012
1	Cytochrome P-450 CYP2E1 (CYP2E1)IBA 09/2012
1	Benzoic Acid (Potassium Benzoate)FDA Link 09/2012
1	NitrosaminesIBA 06/2012
1	Biomarkers (Surrogate Marker)IBA 01/2012
1	Celecoxib (Celebrex)FDA Link 01/2012
1	Plicamycin FDA Link 01/2012
1	Fatty Acid Synthases (Fatty Acid Synthase)IBA 09/2011
1	EnzymesIBA 09/2011
1	MetalloproteinsIBA 09/2011
1	Androgen Receptors (Androgen Receptor)IBA 09/2011
1	TeaIBA 09/2011
1	IntegrinsIBA 09/2011
1	Cytochrome P-450 CYP1A1 (CYP1A1)IBA 09/2011
1	Protein Isoforms (Isoforms)IBA 09/2011
1	PolyphenolsIBA 09/2011
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 07/2011
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2011
1	NS 1619IBA 10/2009
1	CalciumIBA 07/2009
1	Small Interfering RNA (siRNA)IBA 07/2009
1	iberiotoxinIBA 07/2009
1	matrigelIBA 07/2009
1	KATP ChannelsIBA 01/2009
1	minoxidil sulfate esterIBA 01/2009
1	Antineoplastic Agents (Antineoplastics)IBA 01/2009
1	Adenosine Triphosphate (ATP)IBA 01/2009
1	Decitabine FDA Link 01/2008
1	CytosineIBA 01/2008
1	NucleosidesIBA 01/2008

Therapy/Procedure

2	Drug Therapy (Chemotherapy) 06/2018 - 07/2009
2	Chemoprevention 09/2012 - 06/2012
2	Therapeutics 01/2012 - 09/2011
1	Radiotherapy 07/2011